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Internet of Things (IoT)–blockchain-enabled pharmaceutical supply chain resilience in the post-pandemicera

Frontiers of Engineering Management Pages 82-95 doi: 10.1007/s42524-022-0233-1

Abstract: During the COVID-19 pandemic, the current operating environment of pharmaceutical supply chain (PSC)investigate the characteristics of PSC, the key aspects affecting PSC, and the challenges faced by PSC in the post-pandemicera.

Keywords： pharmaceutical supply chain Internet of Things blockchain resilience post-pandemic era

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Special issue: Advancing supply chain resilience for excellence in the post-pandemic era

Frontiers of Engineering Management 2023, Volume 10, Issue 1, Pages 1-4 doi: 10.1007/s42524-022-0246-9

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Digital twin for healthy indoor environment: A vision for the post-pandemic era

Frontiers of Engineering Management 2023, Volume 10, Issue 2, Pages 300-318 doi: 10.1007/s42524-022-0244-y

Abstract: The COVID-19 pandemic and the increased public health awareness have further elevated the urgency for

Keywords： digital twin healthy indoor environment building information modeling occupant–building interaction COVID-19

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Advancing food supply chain resilience in the post-pandemic era

Frontiers of Engineering Management Pages 107-120 doi: 10.1007/s42524-022-0232-2

Abstract: In the post-pandemic era, food supply chains and firms therein are facing unprecedented severe challengesTo survive under the pandemic, retailers have adopted different sourcing strategies, such as contingent

Keywords： food supply chain blockchain contingent sourcing supply chain resilience

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Thoughts on China’s Integrated Circuit Chip Manufacturing in the Post-Moore Era

Hanming Wu, Feijun Zheng

Engineering 2023, Volume 23, Issue 4, Pages 33-39 doi: 10.1016/j.eng.2022.07.021

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CROP PROTECTION OPENS UP NEW ERA OF CONSERVATION AND UTILIZATION OF GREEN OPTIONS

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1, Pages 1-3 doi: 10.15302/J-FASE-2021431

Abstract: in this issue will help broaden reader’s perspectives on every increasing prospect for a new era

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Wheat research and breeding in the new era of a high-quality reference genome

Rudi APPELS

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 3, Pages 225-232 doi: 10.15302/J-FASE-2019265

Abstract:

The publications of the International Wheat Genome Sequencing Consortium (IWGSC) released in August 2018 are reviewed and placed into the context of developments arising from the availability of the high-quality wheat genome assembly.

Keywords： assembly technology molecular markers polyploidy transcript networks wheat genome

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Repercussions of COVID-19 pandemic on solid waste generation and management strategies

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1407-5

Abstract:

• Implication of COVID-19 on medical waste and MSW generation is studied.

Keywords： COVID-19 Medical waste Personal protective equipment Municipal solid waste Waste management

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Platform governance in the era of AI and the digital economy

Frontiers of Engineering Management 2023, Volume 10, Issue 1, Pages 177-182 doi: 10.1007/s42524-022-0241-1

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How do digital technologies improve supply chain resilience in the COVID-19 pandemic?

Frontiers of Engineering Management Pages 39-50 doi: 10.1007/s42524-022-0230-4

Abstract: Digital technologies (DTs) can assist businesses in coping with supply chain (SC) disruptions caused by unpredictability, such as pandemics. However, the current knowledge of the relationship between DTs and supply chain resilience (SCR) is insufficient. This study draws on information processing theory to develop a serial mediation model to address this deficiency. We analyze a sample set consisting of 264 Chinese manufacturers. The empirical results reveal that digital supply chain platforms (DSCPs), as well as supply chain traceability (SCT) and supply chain agility (SCA), fully mediate the favorable association between DTs and SCR. Specifically, the four significant indirect paths indicated that firms can improve SCR only if they use DTs to directly or indirectly improve SCT and SCA (through DSCPs). Our study contributes to the literature on resilience by examining the possible mechanism of mediation through which DTs influence SCR. The findings also offer essential insights for firms to modify their digital strategies and thrive in a turbulent environment.

Keywords： digital technologies supply chain resilience information processing theory COVID-19 China

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Efficacy and safety of JAK inhibitor INC424 in patients with primary and post-polycythemia vera or post-essential

Xin Du,Daobin Zhou

Frontiers of Medicine 2016, Volume 10, Issue 4, Pages 437-443 doi: 10.1007/s11684-016-0472-9

Abstract:

A phase II study (A2202) was performed to evaluate the efficacy and safety of JAK inhibitor ruxolitinib in 63 Chinese MF patients. Ruxolitinib was given twice a day (bid) at a starting dose of 15 mg (n=25) or 20 mg (n=38) based on a baseline platelet count. About 94.7% of the patients achieved a reduction in spleen size, 27.0% of which exhibited significant reduction (≥35%) at week 24. Significant improvement in debilitating constitutional symptoms, as assessed by MFSAF v2.0, was observed in patients treated with ruxolitinib. Ruxolitinib treatment was generally well tolerated by Chinese patients. Although the treatment was associated with an increase in certain adverse events (AEs) that were established as identified risks (anemia and thrombocytopenia), these AEs were considered manageable in this clinical setting. Ruxolitinib provided substantial reductions in splenomegaly and improvements in symptoms, and was well-tolerated by Chinese patients with MF.

Keywords： JAK ruxolitinib Chinese patients myelofibrosis

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Managing supply chain resilience in the era of VUCA

Ying GAO , Zhuo FENG , Shuibo ZHANG

Frontiers of Engineering Management 2021, Volume 8, Issue 3, Pages 465-470 doi: 10.1007/s42524-021-0164-2

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Pandemic Scrambles the Semiconductor Supply Chain

Mitch Leslie

Engineering 2022, Volume 9, Issue 2, Pages 10-12 doi: 10.1016/j.eng.2021.12.006

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Holistic integrative medicine: toward a new era of medical advancement

Daiming Fan

Frontiers of Medicine 2017, Volume 11, Issue 1, Pages 152-159 doi: 10.1007/s11684-017-0499-6

Abstract:

Medicine has encountered unprecedented problems associated with changes in nature, society, and environment, as well as with new human quests for survival, longevity, and health. In the meantime, the development of medicine is facing challenges that resulted from the over-division and specialization of disciplines and the fragmentation of medical knowledge. To construct a new medical system that is more suitable for human health and disease treatment, holistic integrative medicine (HIM), which regards the human body as a holistic entity, organically integrates the most advanced knowledge and theories in each medical field and the most effective practices in various clinical specialties to revise and adjust on the basis of social, environmental, and psychological conditions. HIM is the inevitable and necessary direction for the future development of medicine. In this article, we illustrated the connotation of HIM, the differences between HIM and other medical conceptions, and the practice of HIM in recent years.

Keywords： holistic integrative medicine precision medicine general practice medicine

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Dynamic modelling and simulation of a post-combustion CO capture process for coal-fired power plants

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 2, Pages 198-209 doi: 10.1007/s11705-021-2057-7

Abstract: Solvent-based post-combustion capture technologies have great potential for CO₂ mitigationComposed by a series of partial differential equations, first-principle post-combustion capture modelsfit properties and simplify the chemical and physical process, based on which a universal and hybrid post-combustion

Keywords： CO₂ capture post-combustion capture simulation dominant factor